form Mark Kelson

Hi Paul,

Here is some R resource that mey be interesting to a clinical trials person.

lme4 package: this fits various hierarchical models

mice package: this has functions for doing loads of things around multiple imputation (a common and preferred method for handling missing data in trials)

pwr package: lots of functions for power calculations

survival package: fits survival analysis

Fun ones

vioplot package: a package I saw recently that fits violin plots to data which I quite like

wesanderson package: a package that provides colour palettes for graphing based on the predominent colours in various Wes Anderson movies

I also attach a document that covers regulatory compliance and validation issues in clinical trials settings for R.

Hope this helps

Mark